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Somatropin (Recombinant Human Growth Hormone, rhGH) API
Product Overview: Somatropin is a peptide hormone secreted by the anterior lobe of the pituitary gland. It promotes the growth of bones, internal organs, and the entire body, stimulates protein synthesis, and influences lipid and mineral metabolism. This product is obtained through secretory expression in Escherichia coli engineered for high-level expression of the hGH gene, followed by fermentation and purification, comprises 191 amino acid residues, and its spatial conformation, amino acid sequence, and physiological and pharmacological actions are identical to those of natural human growth hormone.   Indications: Growth retardation in children due to endogenous growth hormone deficiency Short stature in children with Noonan syndrome Short stature or growth retardation in children with SHOX gene deficiency Growth retardation in children with Prader-Willi syndrome (PWS) Idiopathic short stature (ISS) Treatment of severe burns Short stature in children with achondroplasia Short bowel syndrome in adults receiving nutritional support Growth retardation in girls with gonadal dysgenesis (Turner syndrome) Short stature in children born small for gestational age (SGA) who have not achieved catch-up growth by age 2 Growth retardation in prepubertal children with chronic kidney disease (CKD) Growth hormone deficiency caused by confirmed hypothalamic-pituitary disease, or marked growth hormone deficiency confirmed by two different growth hormone stimulation tests
  • Chinese Pinyin : Ren Shengzhangjisu Yuanliaoyao
  • Molecular Formula : C990H1528N262O300S7
  • CAS : 12629-01-5
  • Molecular Weight : 22125Da
  • Traits : Appearance: White lyophilized powder or bulk solution
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